Dr. Joseph Warren’s medical account book.
Dr. Joseph Warren (June 11, 1741 – June 17, 1775) was an American doctor who played a leading role in American Patriot organizations in Boston in early days of the American Revolution, eventually serving as president of the revolutionary Massachusetts Provincial Congress. Warren enlisted Paul Revere and William Dawes on April 18, 1775, to leave Boston and spread the alarm that the British garrison in Boston was setting out to raid the town of Concord and arrest rebel leaders John Hancock and Samuel Adams.
Lepers Attended by Angels, Neapolitan School, 17th Century.
Dr. Walker was the first female surgeon in the U.S. Army, serving during the Civil War.
She was awarded the Medal of Honor in 1865 by President Johnson, and remains the only woman to have ever won it, to this date. Interestingly, this high honor was awarded to her (and even had a bill passed in order to make her eligible) in order to recognize her service to the country…while making sure that she didn’t receive an army commission in retirement.
Indeed, she made less as a pensioner than the widows of most officers did, but she saw the greater honor of her Medal, wearing it every day until her death in 1917.
Walker also campaigned as an abolitionist (prior to the war), prohibitionist, and an advocate for dress reform, citing women’s clothing as “immodest and unwieldy”. She was arrested several times in the late 1800s for “impersonating a man”, because of her trousers and top hat.
Fall of the Angels at St. Michael’s Church in Vienna, Austria
Primary adrenal deficiency, or Addison’s disease, results in a deficiency of both mineralocorticoids and glucocorticoids. This can lead to vague weakness or orthostatic hypotension that later progresses to electrolyte abnormalities (low Na, high K), nausea/vomiting, abdominal pain and ultimately hypotension, wasting and death. Hyperpigmentation (picture above) occurs due to low cortisol prompting increased pituitary ACTH and increased blood Beta-lipotropin which has melanocyte stimulating activity.
In secondary adrenal insufficiency (such as from pituitary insufficiency), electrolytes will often be normal and hyperpigmentation absent.
Info from Merck Manual
Doña Isabel la Católica dictando su testamento de Eduardo Rosales (1868).
A rare disease of the tropics, conidiobolomycosis aka rhinoentomophthoromycosis is a subcutaneous zygomycosis (fungal infection) that can dramatically alter the features of the face and lead to the alienation of individuals from their society.